SCWRL SCWRL is a program for adding sidechains to a protein backbone based on a backbone-dependent rotamer library. The library provides lists of chi1-chi2 pairs for residues at given phi-psi values, and explores these pairs to try to minimize sidechain- backbone clashes and sidechain-sidechain clashes. You may get output from the program at any of three steps (best library rotamers, no clashes relieved; backbone clashes relieved; backbone and sidechain-sidechain clashes relieved). Preliminary studies show prediction of chi1 correct for all residues on native backbones is 77%. Chi3 and chi4 are built in extended conformations.

Current Version:   1.0 License Type:   Free for Academic Use.

Home Site: http://www.cmpharm.ucsf.edu/~bower/scwrl/scwrl.html Source Code Availability:   Yes, (contact Steve Sizemore) Available Binary Packages: Debian Package:   No RedHat RPM Package:   No Other Packages:   No Targeted Platforms: Binary available for SGI. The authors of SCWRL think SCWRL may compile alright under Linux, since it doesn't use any SGI graphics. Software/Hardware Requirements: C compiler

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